Cryptosporidium hominis

Taxonomy: Eukaryota; Alveolata; Apicomplexa; Coccidia; Eimeriida; Cryptosporidiidae; Cryptosporidium

Source: http://www.hominis.mic.vcu.edu/

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Cryptosporidium hominis, along with Cryptosporidium parvum, is among the medically important Cryptosporidium species. It is an obligate parasite of humans that can colonize the gastrointestinal tract resulting in the gastroenteritis and diarrhea characteristic of cryptosporidiosis. Unlike C. parvum, which has a rather broad host range, C. hominis is almost exclusively a parasite of humans. As a result, C. hominis has a low zoonotic potential compared to C. parvum. It is spread through the fecal-oral route usually by drinking water contaminated with oocyst laden feces. There are many exposure risks that people can encounter in affected areas of the world. Cryptosporidium infections are large contributors of child death and illness in heavily effected areas, yet low importance has been placed on both identifying the species and finding more treatment options outside of nitazoxanide for children and AIDS patients.

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Proteome Quality Index Information

Scoring Method Raw Score Metric Rating
X content 0.0236 0.023617 0.637526
CEG Domain Combination Homology 0.2705 0.270531 0.055614
Percent of Sequences covered 29.0000 1.893180 0.279833
Number of Superfamilies 503.0000 2.262908 0.330702
Average Sequence Length 450.0000 1.630506 0.309803
Average hit length 280.0000 2.388435 0.231406
Number of Families 236.0000 1.909840 0.355749
Number of Unique Architectures 969.0000 1.660458 0.398724
Percent with Assignment 46.0000 0.132219 0.952662
Percent of sequences in Uniprot 96.6500 96.650000 0.891343
DOGMA 35.6700 35.670000 0.337019

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